CD40 Ligand

A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1.

Also Known As:

CD40L; Antigen, CD154; CD154 Antigen; T-B Cell Activating Molecule; TNF Superfamily, Member 5; gp39 Antigen, T-Cell; T-Cell gp39 Antigen; gp39 Antigen, T Cell; Antigens, CD154; CD154 Antigens; Tumor Necrosis Factor Ligand Superfamily Member 5

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - CD40 Ligand: 2256
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Tumor Necrosis Factors: 155
        CD40 Ligand: 2256
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - CD40 Ligand: 2256
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - CD40 Ligand: 2256
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Tumor Necrosis Factors: 155
        CD40 Ligand: 2256
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - Cytokines: 168239
    - Tumor Necrosis Factors: 155
      - CD40 Ligand: 2256

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Disease

Drug/Important Bio-Agent (IBA)